- Vom Anfall zur Therapieentscheidung: anfallssuppressive Medikamente in der klinischen PraxisFür die pharmakologische Behandlung epileptischer Anfälle steht ein breites Spektrum an ASM zur Verfügung. Die Auswahl des geeigneten Wirkstoffs orientiert sich primär an der Art der Epilepsie (fokal vs. generalisiert), dem zugrunde liegenden …
- Fieberkrämpfe in der PädiatrieEs gibt einige Faktoren, die das Auftreten von FK bei einer Gruppe von Kindern begünstigen, hier sind sich die Leitlinien der AWMF, NICE und AAP einig. Die Genese scheint multifaktoriell zu sein, die genaue Ätiologie ist nicht geklärt. Da eine …
- Diagnose und Differenzialdiagnose erster afebriler Anfälle im Kindes- und JugendalterAfebrile Anfälle im Kindes- und Jugendalter erfordern aufgrund ihrer heterogenen Ätiologie und Prognose einen individuellen diagnostischen und therapeutischen Zugang. Sie können Ausdruck einer akuten systemischen oder zerebralen Störung (akut …
- Prehospital treatment of seizure clusters and status epilepticus. English versionThe treatment of SE follows a stepwise approach. In addition to antiseizure therapy, causal treatment should also be carried out whenever possible (Fig. 1 ; [ 1 , 4 ]). Fig. 1 Stepwise treatment of status epilepticus ( SE ) according to German …
- Seizure worsening in SCN1A-associated Dravet syndrome while on cenobamate: case series and literature review. English versionWe report on two patients with genetically confirmed DS who were treated with CNB at our centers. The case reports were prepared in accordance with CARE guidelines [ 16 ]. The diagnosis of DS was made on the basis of the current International …
- First epileptic seizure in youth and adulthoodSeizures are the third most common reason for presentation to the neurological emergency department. The diagnosis and management of (first) seizures are therefore of great importance in every neurology department. In this article, we provide an …
- Pharmacotherapy of seizures in neonates. English versionSeizures are the most frequent neurological emergency in neonates. Neonatal seizures are mostly acutely provoked but in ca. 15% they can be the primary manifestation of an epilepsy with neonatal onset. With regards to antiseizure medication …
- Neonatal developmental and epileptic encephalopathies. English versionThe International League Against Epilepsy (ILAE) distinguishes three main groups of neonatal epilepsy syndromes: (1) self-limiting neonatal, neonatal-infantile and infantile (familial or not familial) epilepsies, (2) developmental and epileptic …
- Long-term effects of invasive and transcutaneous vagus nerve stimulation in patients with epilepsy: a retrospective cohort studyFor patients with drug-resistant epilepsy who are not eligible for epilepsy surgery, neuromodulation is a viable treatment option. Besides invasive treatments such as invasive vagus nerve stimulation (iVNS), deep brain stimulation, and responsive …
- Long-term outcome following neonatal seizures. English versionEpileptic seizures are among the most common neurological manifestations in the neonatal period. A distinction is made between acute symptomatic (provoked) and unprovoked neonatal seizures: the former arise from brain injuries, such as …