- Seizure worsening in SCN1A-associated Dravet syndrome while on cenobamate: case series and literature review. English versionWe report on two patients with genetically confirmed DS who were treated with CNB at our centers. The case reports were prepared in accordance with CARE guidelines [ 16 ]. The diagnosis of DS was made on the basis of the current International …
- First epileptic seizure in youth and adulthoodSeizures are the third most common reason for presentation to the neurological emergency department. The diagnosis and management of (first) seizures are therefore of great importance in every neurology department. In this article, we provide an …
- Pharmacotherapy of seizures in neonates. English versionSeizures are the most frequent neurological emergency in neonates. Neonatal seizures are mostly acutely provoked but in ca. 15% they can be the primary manifestation of an epilepsy with neonatal onset. With regards to antiseizure medication …
- Neonatal developmental and epileptic encephalopathies. English versionThe International League Against Epilepsy (ILAE) distinguishes three main groups of neonatal epilepsy syndromes: (1) self-limiting neonatal, neonatal-infantile and infantile (familial or not familial) epilepsies, (2) developmental and epileptic …
- Long-term effects of invasive and transcutaneous vagus nerve stimulation in patients with epilepsy: a retrospective cohort studyFor patients with drug-resistant epilepsy who are not eligible for epilepsy surgery, neuromodulation is a viable treatment option. Besides invasive treatments such as invasive vagus nerve stimulation (iVNS), deep brain stimulation, and responsive …
- Diagnosis and classification of neonatal seizures. English versionEpileptic seizures are the most frequent neurological emergency in the neonatal period. In contrast to seizures in older children and adults they are mostly acute symptomatic seizures as a response to a prenatal or perinatal acute brain injury; …
- Long-term outcome following neonatal seizures. English versionEpileptic seizures are among the most common neurological manifestations in the neonatal period. A distinction is made between acute symptomatic (provoked) and unprovoked neonatal seizures: the former arise from brain injuries, such as …
- More than epilepsy—a parent-initiated collaborative analysis of the research landscape and research needs in Dravet syndromeThis landscape analysis was initiated and sponsored by three patient and family associations (PFAs) for DS: the Gruppo Famiglie Dravet Associazione APS (Milan, Italy), the Vereinigung Dravet Syndrom Schweiz (Zurich, Switzerland), and the Dravet …
- Mahmut Gazi Yaşargil (1925–2025)Mahmut Gazi Yaşargil passed away just 3 weeks before his 100th birthday. “He has not only been a brilliant surgeon and physician of highest moral standards, but also an exceptional teacher”—This statement was made by Yaşargil in 1984 in …
- Des Pudels Kern: Differenzierung epileptischer Anfälle von nicht-epileptischen EreignissenEpileptische Anfälle sind Voraussetzung für die Diagnose einer Epilepsie. Vor Diagnosestellung und Behandlungsbeginn muss sorgfältig abgewogen werden, ob für die paroxysmal auftretenden Störungen auch andere Ursachen verantwortlich sein könnten.