SERENE

SERENE is the Swiss Epilepsy Research Network, founded by the Swiss League Against Epilepsy in 2019. SERENE is open to all members of the Swiss Epilepsy League who conduct scien­tific research into epilepsy in Switzerland.

SERENE wants to strengthen epilepsy research in Switzer­land through collab­o­ra­tion. One of its aims is to improve access to research-relevant data throughout Switzer­land (in line with the provi­sions of data protec­tion and ethics commis­sions). Members present new research projects on meetings during major neuro­log­ical conven­tions in Switzer­land, or online.

Benefits to SERENE members

  • Access to a broad network of Swiss epilepsy researchers that improves exchange and avoids redundancies
  • Help in finding partners for multi-centre projects and recruiting patients for studies
  • Provi­sion of advice and feedback concerning funding
  • Newsletter keeping members up to date

Current projects

Project (click to download PDF)
Insti­tu­tion / Contact
In search of IRB Status
Forecasting seizure risk over days using chronic EEG recordings e‑Lab Bern Univer­sity / UCSF - Approved Almost completed
Probing cortical excitability in patients implanted with icEEG e‑Lab Bern Univer­sity / Inselspital Patients Approved Ongoing 2019–2022
Seizures-on-demand: Mouse model of seizures that are triggered using optogenetics e‑Lab Bern Univer­sity / Inselspital - Approved Ongoing 2019–2022
Minimally invasive chronic EEG: Clinical trial of sub-scalp device e‑Lab Bern Univer­sity / Insel­spital / Wyss Center Patients Pending Ongoing 2020–2022
Inter­ac­tions between spatio-temporal epileptic network and memory networks in humans EEG and Epilepsy Unit, HUG, Univer­sity of Geneva  Patients Pending Pilots
Markers of epileptic activity in simul­ta­neous scalp and intracra­nial EEG EEG and Epilepsy Unit, HUG, Univer­sity of Geneva  Partners Approved Ongoing
Source and network analyses of epileptic activity during wakeful­ness and sleep EEG and Epilepsy Unit, HUG, Univer­sity of Geneva  Partners Pending Starting
Trimodal charac­ter­i­za­tion of struc­tural and functional brain connec­tivity in focal epilepsy using concur­rent EEG-fMRI and tractography EEG and Epilepsy Unit, HUG, Univer­sity of Geneva  Patients, Partners Approved Ongoing
“PRESUDE” Brain­stem MRI biomarker to PREdict the risk of Sudden Unexpected Death in Epilepsy Service de Neurologie, CHUV, Lausanne Partners Approved Ongoing
Inves­ti­gating the effects of closed-loop auditory stimu­la­tion on sleep and behavior in children with sleep-dependent epilepsy Univer­sity Children’s Hospital Zurich Patients Approved Recruit­ment
Electro­phys­i­o­log­ical recording of high frequency oscil­la­tions (HFO) to charac­terize epilep­to­genic brain tissue in patients Univer­sitätsSpital Zürich, Klinik für Neurochirurgie Partners Approved Funded, ongoing
The connec­tivity and anatomy of the poste­rior hippocampal commis­sure in Humans Univer­sitätsspital Zürich, Klinik für Neurochirurgie - Approved Almost completed
Cogni­tive profile in elderly epileptic patients treated with peram­panel as first add-on Neuro­centro della Svizzera Italiana, Lugano  Partners Planned Appli­ca­tion for funding
CERTA “Contin­uous EEG Random­ized Trial in Adults” CHUV, Lausanne Partners Approved Data analyses ongoing
Thera­peutic drug monitoring of newer gener­a­tion antiepileptic drugs CHUV, Lausanne (Partners) Approved Data collected, currently analysing data
Swiss First Insel­spital, Bern; HUG, Geneva - Approved Ongoing
SEVERITY: Quanti­fying the severity of gener­al­ized tonic-clonic seizures (GTCS) with connected devices Service de Neurologie, CHUV, Lausanne Partners Approved recruit­ment ongoing

Partic­i­pating institutions

  • Neurol­o­gische Univer­sität­sklinik, Univer­sitätsspital Basel
  • Universitäts-Kinderspital beider Basel UKBB
  • Univer­sitätsin­stitut für Neuro­ra­di­ologie, Insel­spital, Bern
  • Schlaf-Wach-Epilepsie-Zentrum SWEZ, Univer­sität­sklinik für Neurologie, Insel­spital, Bern
  • Unité d’épileptologie/EEG, Hôpitaux Univer­si­taires de Genève (HUG)
  • Unité de Neuropé­di­a­trie, Hôpitaux Univer­si­taires de Genève (HUG)
  • Service de Neurologie, CHUV, Lausanne
  • Unité de Neuropé­di­a­trie, CHUV, Lausanne
  • Insti­tu­tion de Lavigny
  • Neuro­centro della Svizzera Italiana, Ospedale Civico, Lugano
  • Service de Neurologie, Hôpital du Valais, Sion
  • Neurol­o­gische Klinik, Kanton­sspital St. Gallen
  • Kinderneu­rol­o­gische Abteilung, Ostschweizer Kinder­spital, St.Gallen
  • Klinik Bethesda, Tschugg
  • Schweiz­erische Epilepsie-Klinik Klinik Lengg, Zürich
  • Universitäts-Kinderklinik, Zürich
  • Kliniken für Neurologie und Neurochirurgie, Univer­sitätsspital Zürich

SERENE is open to further insti­tu­tions (research insti­tu­tions, other hospi­tals) as well as individual basic/translational scien­tists, neuropsy­chol­o­gists, nurses, social workers, physical, occupa­tional and speech thera­pists, etc. 

Contact SERENE

Advice concerning funding from foundations

Hints from Swiss­Foun­da­tions (D/F) Fundraiso.ch Special service to SERENE members: feedback on founda­tion applications

Last updated: July 2021