SERENE is the Swiss Epilepsy Research Network, founded by the Swiss League Against Epilepsy in 2019. SERENE is open to all members of the Swiss Epilepsy League who conduct scien­tific research into epilepsy in Switzerland.

SERENE wants to strengthen epilepsy research in Switzer­land through collab­o­ra­tion. One of its aims is to improve access to research-relevant data throughout Switzer­land (in line with the provi­sions of data protec­tion and ethics commis­sions). Members present new research projects on meetings during major neuro­log­ical conven­tions in Switzer­land, or online.

Benefits to SERENE members

  • Access to a broad network of Swiss epilepsy researchers that improves exchange and avoids redundancies
  • Help in finding partners for multi-centre projects and recruiting patients for studies
  • Provi­sion of advice and feedback concerning funding
  • Newsletter keeping members up to date

Current projects

Project (click to download PDF)
Insti­tu­tion / Contact
In search of IRB Status
Forecasting seizure risk over days using chronic EEG recordings e‑Lab Bern Univer­sity / UCSF - Approved Almost completed
Probing cortical excitability in patients implanted with icEEG e‑Lab Bern Univer­sity / Inselspital Patients Approved Ongoing 2019–2022
Seizures-on-demand: Mouse model of seizures that are triggered using optogenetics e‑Lab Bern Univer­sity / Inselspital - Approved Ongoing 2019–2022
Minimally invasive chronic EEG: Clinical trial of sub-scalp device e‑Lab Bern Univer­sity / Insel­spital / Wyss Center Patients Pending Ongoing 2020–2022
Inter­ac­tions between spatio-temporal epileptic network and memory networks in humans EEG and Epilepsy Unit, HUG, Univer­sity of Geneva  Patients Pending Pilots
Markers of epileptic activity in simul­ta­neous scalp and intracra­nial EEG EEG and Epilepsy Unit, HUG, Univer­sity of Geneva  Partners Approved Ongoing
Source and network analyses of epileptic activity during wakeful­ness and sleep EEG and Epilepsy Unit, HUG, Univer­sity of Geneva  Partners Pending Starting
Trimodal charac­ter­i­za­tion of struc­tural and functional brain connec­tivity in focal epilepsy using concur­rent EEG-fMRI and tractography EEG and Epilepsy Unit, HUG, Univer­sity of Geneva  Patients, Partners Approved Ongoing
“PRESUDE” Brain­stem MRI biomarker to PREdict the risk of Sudden Unexpected Death in Epilepsy Service de Neurologie, CHUV, Lausanne Partners Approved Ongoing
Inves­ti­gating the effects of closed-loop auditory stimu­la­tion on sleep and behavior in children with sleep-dependent epilepsy Univer­sity Children’s Hospital Zurich Patients Approved Recruit­ment
Electro­phys­i­o­log­ical recording of high frequency oscil­la­tions (HFO) to charac­terize epilep­to­genic brain tissue in patients Univer­sitätsSpital Zürich, Klinik für Neurochirurgie Partners Approved Funded, ongoing
The connec­tivity and anatomy of the poste­rior hippocampal commis­sure in Humans Univer­sitätsspital Zürich, Klinik für Neurochirurgie - Approved Almost completed
Cogni­tive profile in elderly epileptic patients treated with peram­panel as first add-on Neuro­centro della Svizzera Italiana, Lugano  Partners Planned Appli­ca­tion for funding
CERTA “Contin­uous EEG Random­ized Trial in Adults” CHUV, Lausanne Partners Approved Data analyses ongoing
Thera­peutic drug monitoring of newer gener­a­tion antiepileptic drugs CHUV, Lausanne (Partners) Approved Data collected, currently analysing data
Swiss First Insel­spital, Bern; HUG, Geneva - Approved Ongoing
SEVERITY: Quanti­fying the severity of gener­al­ized tonic-clonic seizures (GTCS) with connected devices Service de Neurologie, CHUV, Lausanne Partners Approved recruit­ment ongoing

Partic­i­pating institutions

  • Neurol­o­gische Univer­sität­sklinik, Univer­sitätsspital Basel
  • Universitäts-Kinderspital beider Basel UKBB
  • Univer­sitätsin­stitut für Neuro­ra­di­ologie, Insel­spital, Bern
  • Schlaf-Wach-Epilepsie-Zentrum SWEZ, Univer­sität­sklinik für Neurologie, Insel­spital, Bern
  • Unité d’épileptologie/EEG, Hôpitaux Univer­si­taires de Genève (HUG)
  • Unité de Neuropé­di­a­trie, Hôpitaux Univer­si­taires de Genève (HUG)
  • Service de Neurologie, CHUV, Lausanne
  • Unité de Neuropé­di­a­trie, CHUV, Lausanne
  • Insti­tu­tion de Lavigny
  • Neuro­centro della Svizzera Italiana, Ospedale Civico, Lugano
  • Service de Neurologie, Hôpital du Valais, Sion
  • Neurol­o­gische Klinik, Kanton­sspital St. Gallen
  • Kinderneu­rol­o­gische Abteilung, Ostschweizer Kinder­spital, St.Gallen
  • Klinik Bethesda, Tschugg
  • Schweiz­erische Epilepsie-Klinik Klinik Lengg, Zürich
  • Universitäts-Kinderklinik, Zürich
  • Kliniken für Neurologie und Neurochirurgie, Univer­sitätsspital Zürich

SERENE is open to further insti­tu­tions (research insti­tu­tions, other hospi­tals) as well as individual basic/translational scien­tists, neuropsy­chol­o­gists, nurses, social workers, physical, occupa­tional and speech thera­pists, etc. 

Contact SERENE

Advice concerning funding from foundations

Hints from Swiss­Foun­da­tions (D/F) Special service to SERENE members: feedback on founda­tion applications

Last updated: July 2021